GenotypeConcordanceSummaryMetrics

Metrics

Category Metrics


Overview

Class that holds summary metrics about Genotype Concordance @author George Grant

This table summarizes the values that are specific to this metric.

Metric Summary
VARIANT_TYPE
The type of the event (i.e. either SNP or INDEL)
TRUTH_SAMPLE
The name of the 'truth' sample
CALL_SAMPLE
The name of the 'call' sample
HET_SENSITIVITY
The sensitivity for all heterozygous variants (Sensitivity is TP / (TP + FN))
HET_PPV
The ppv (positive predictive value) for all heterozygous variants (PPV is the TP / (TP + FP))
HET_SPECIFICITY
The specificity for all heterozygous variants cannot be calculated
HOMVAR_SENSITIVITY
The sensitivity for all homozygous variants (Sensitivity is TP / (TP + FN))
HOMVAR_PPV
The ppv (positive predictive value) for all homozygous variants (PPV is the TP / (TP + FP))
HOMVAR_SPECIFICITY
The specificity for all homozygous variants cannot be calculated.
VAR_SENSITIVITY
The sensitivity for all (heterozygous and homozygous) variants (Sensitivity is TP / (TP + FN))
VAR_PPV
The ppv (positive predictive value) for all (heterozygous and homozygous) variants (PPV is the TP / (TP + FP))
VAR_SPECIFICITY
The specificity for all (heterozygous and homozygous) variants (Specificity is TN / (FP + TN))
GENOTYPE_CONCORDANCE
The genotype concordance for all possible states. Genotype Concordance is the number of times the truth and call states match exactly / all truth and call combinations made
NON_REF_GENOTYPE_CONCORDANCE
The non-ref genotype concordance, ie for all var states only. Non Ref Genotype Concordance is the number of times the truth and call states match exactly for *vars only* / all truth and call *var* combinations made

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